Search results for "Multicystic dysplastic kidney . Antiepileptic drugs . Major congenital anomalies . Infant"

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Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy

2007

Prenatal exposure to antiepileptic drugs (AEDs) increases the risk of major congenital malformations (MCM) in the fetus. AED-related abnormalities include heart and neural tube defects, cleft palate, and urogenital abnormalities. Among the various congenital anomalies of the kidney and urinary tract (CAKUT), multicystic dysplastic kidney (MCDK) disease is one of the most severe expressions. Although prenatal ultrasound (US) examination has increased the prenatal diagnosis of MCDK, the pathogenesis is still unclear. We report on four cases of MCDK in infants of epileptic women treated with AEDs during pregnancy. From October 2003 to June 2006, we observed four infants with unilateral MCDK bo…

Nephrologymedicine.medical_specialtyTime FactorsVoiding cystourethrogramUrinary systemMulticystic dysplastic kidneyPrenatal diagnosisUltrasonography PrenatalPregnancyInternal medicineProhibitinsmedicineHumansMulticystic Dysplastic KidneyMaternal-Fetal ExchangeFetusPregnancyEpilepsymedicine.diagnostic_testbusiness.industryObstetricsInfant Newbornmedicine.diseaseSurgeryMulticystic dysplastic kidney . Antiepileptic drugs . Major congenital anomalies . InfantCarbamazepineTreatment OutcomeNephrologyPhenobarbitalPrenatal Exposure Delayed EffectsPediatrics Perinatology and Child HealthGestationAnticonvulsantsFemalebusinessFollow-Up Studies
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